Cascade reactions in multicompartmentalized polymersomes.
نویسندگان
چکیده
Enzyme-filled polystyrene-b-poly(3-(isocyano-L-alanyl-aminoethyl)thiophene) (PS-b-PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene-b-poly(ethylene oxide) (PB-b-PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An original cofactor-dependent three-enzyme cascade reaction is performed, using either compatible or incompatible enzymes, which takes place across multiple compartments.
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 53 1 شماره
صفحات -
تاریخ انتشار 2014